中国人民解放军总医院第一医学中心放射治疗科;
目的：定量分析瓦里安Ethos自适应放射治疗(ART)系统上基于滤波反投影(FBP)和迭代重建(IR)技术的锥形束CT(CBCT)和迭代CBCT(iCBCT)的图像质量以及合成伪CT(sCT)的差异。方法：利用CT图像质量测试专用Catphan604模体，基于胸部扫描和腹部扫描完成CBCT和iCBCT各5次扫描，获取4套图像，每套图像包括CBCT图像、基于CBCT合成的sCT、iCBCT图像、基于iCBCT合成的sCT，分析其噪声功率谱(NPS)、图像均匀性指数(UI)、调制传递函数(MTF)、低对比度可见度(LCV)和对比度噪声比(CNR)。回顾性选取2023年8月至2024年5月解放军总医院第一医学中心收治的6例临床放疗患者，使用胸部扫描和腹部扫描获取6例患者的图像，分析基于CBCT和iCBCT图像形变配准所得sCT图像，并与定位CT图像进行对比，定量分析其绝对误差(MAE)和均方根误差(RMSE)。结果：iCBCT与CBCT相比，胸部图像NPS显著降低0.08，腹部图像降低0.06;iCBCT胸部、腹部图像UI分别为0.37和0.28,CBCT分别为0.65和0.39;iCBCT胸部、腹部图像LCV分别为0.67和0.56,CBCT分别为0.93和0.90;MTF50%除腹部iCBCT是0.29 lp/mm外，其余均为0.28 lp/mm,iCBCT和CBCT图像高对比度分辨率基本一致。基于CBCT和iCBCT生成的sCT与定位CT的相似度分析差异均无统计学意义(P>0.05)。结论：iCBCT图像质量优于传统CBCT，而基于CBCT和iCBCT生成的sCT，其CT值准确性皆符合要求，均可用于ART的剂量计算。
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基本信息:
DOI：
中图分类号:R730.55
引用信息:
[1]刘晓宇,寇宇涵,阎长鑫等.基于Ethos自适应放射治疗系统不同成像算法的图像质量分析[J].中国医学装备,2024,21(11):1-6.
基金信息:
国家重点研发计划(2022YFC2409502,2022YFC2409503)~~